Eritrea opened their qualifying campaign with a draw against Kenya.
Hesham Yakan is leading Eritrea as the country's first foreign head coach in 18 years.
Eritrea have remained unbeaten in Yakan's first three matches in charge.
Yonathan Sultan is listed in Eritrea's predicted XI after starting the Kenya match.

Eritrea predicted formation: 4-2-3-1

Eritrea predicted XI: Yonathan Sultan; Fors, Misignha, Embaye, Idris; Tekie, Girmai; Yohannes, Teklezgi, Gerezgiher; Sulieman

South Africa predicted formation: 4-2-3-1

South Africa predicted XI: Williams; Sebelebele, Okon, Makhanya, Kabini; Sithole, Mokoena; Maseko, Mofokeng, Appollis; Rayners